Runx2 Contributes to the Regenerative Potential of the Mammary Epithelium
Researchers investigated the role of Runx2 in the mammary stem/progenitor population and its relationship with WNT signaling. They showed that RUNX2 protein is differentially expressed throughout embryonic and adult development of the murine mammary gland with high levels of expression in mammary stem-cell enriched cultures. [Sci Rep] Full Article
Biological Markers of Invasive Breast Cancer
In recent years, gene expression profiling has made the molecular classification of breast cancer possible. Classification of breast cancer by immunohistochemical expression of estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 and Ki-67 is standard practice for clinical decision-making. [Jpn J Clin Oncol] Abstract
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Stem Cell Researcher Min Yu Receives the NIH’s New Innovator Award
As a winner of the NIH Director’s New Innovator Award, USC Stem Cell principal investigator Min Yu will strive to develop individualized medicine targeting rare and deadly breast cancer stem cells. The five-year, $2.475 million award is part of the High-Risk, High-Reward Research program supported by the NIH Common Fund. [Keck School of Medicine of USC] Press Release
Do Stem Cells Hold the Key to Breast Cancer Spread?
A $680,000 investment in breast cancer research is helping Dr. Ewa Michalak to find the stem cells that hold the key to how breast cancer spreads, and could lead to better treatments for the disease. [The Walter and Eliza Hall Institute of Medical Research] Press Release
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